3 Safest SARMs for Bodybuilding: Safe and Effective Muscle Growth

SARMs have gained popularity in the fitness community for their ability to accelerate muscle growth and optimize performance. Some studies suggest that SARMs offer benefits such as heightened vascularity and amplified lean mass.

However, more research is needed to fully understand their effects and potential risks, especially regarding building lean body mass. It’s crucial to consult with healthcare professionals before considering the use of SARMs. Additionally, they contribute to enhanced athletic performance.

Various studies, including one by Tomas Koller, have highlighted potential liver injuries associated with the use of selective androgen receptor modulators. It’s essential to consider a broad spectrum of research and consult healthcare professionals when evaluating the risks and benefits of SARMs.

In this guide, we’ll explore the three best SARMs that offer benefits, dosage, cycle, and side effects, backed by scientific research and user experiences.

Are SARMs Safe for Bodybuilding?

Are SARMs Safe for Bodybuilding?

SARMs are safe for human consumption for bodybuilding if used according to proper guidelines. But, they carry the potential for severe risks like stroke and heart attack if you overdo it. Until regulated products with clinical safety information are available, it’s best to avoid products marketed as containing SARMs. There are safer, more proven dietary supplements available to help you reach your fitness goals.

The U.S Food and Drug Administration (FDA) has not approved any SARM for human use, and they are not legal as dietary supplements. They may be available for research purposes. It’s crucial to stay updated on the guidelines and legal status of SARMs usage. For more information, refer to the FDA’s statement on SARMs [FDA’s statement]

3 Safest SARMs for Bodybuilding

Below we discuss the 3 Safest SARMs of Testolone RAD-140, Ibutamoren MK-677, and Ligandrol LGD-4033 for bodybuilders:

MYO RAD 140 Testolone

MYO RAD 140 Testolone

MYO RAD 140 Testolone is a Selective Androgen Receptor Modulator, often referred to as Testolone. It’s making waves in the bodybuilding community for its remarkable capacity to increase muscle mass, enhance strength, and facilitate fat loss. Unlike some more aggressive SARMS, its side effects are relatively mild, but post-cycle therapy (PCT) may still be a consideration.

Testolone Overview

An overview table with essential features of MYO RAD 140 Testolone is given below:

FeaturesRAD 140 Testolone
Mechanism of ActionBinds to androgen receptors in the body, particularly in muscles and bones, with the goal of increasing muscle mass and bone density without significantly affecting other tissues.
Common UsesTo gain muscle mass while bulking and reduce muscle wasting while cutting
Dosage10 to 20mg per day
Cycle Length8-12 weeks
StakesMK-677 Ibutamoren
BenefitsIt enhances lean muscle tissue, strength, and fat loss, boosts energy endurance and improves cognitive function.
Side EffectsMood swings, hair loss, acne, increased anxiety, aggression, and hormonal imbalances.
Men / WomenYes
PCT RequirementYes
Price89.99 CAD


  1. Massive muscle gains
  2. Lean muscle mass preservation
  3. Accelerated fat burning
  4. Heightened energy levels
  5. Rapid recovery


  1. Liver Injury
  2. Hormonal Imbalance
  3. Cardiovascular Risks

MYO HGH Ibutamoren Mk 677

MYO HGH Ibutamoren Mk 677

Ibutamoren MK-677 restores nitrogen balance, preventing muscle loss and facilitating the rapid development of lean muscle mass flawlessly. This SARM has a remarkable appetite-boosting effect, making it a favourite among those looking to pack on size and strength.

Mk 677 Overview Table

An overview table with essential features of MYO HGH Ibutamoren Mk 677 is given below:

FeaturesIbutamoren Mk 677
Mechanism of ActionBinds to ghrelin receptors in the brain, leading to increased GH and IGF-1 secretion. Enhanced muscle growth, improved bone density, and better sleep quality.
Common UsesIncrease lean body mass in bodybuilders and athletes.
Dosage10mg per day
Cycle Length8 weeks
BenefitsGrowth hormone secretagogue enhances muscle growth, improves bone density, boosts metabolism, and increases appetite.
Side EffectsWater retention, joint pain, fatigue, and mild muscle pain
Men / WomenBoth
PCT RequirementYes
Price89.99 CAD


  1. Explosive Muscle Growth
  2. Enhanced Fat Loss
  3. Enhanced Bone Density
  4. Increased Energy Levels
  5. Long-lasting Results


  1. Lethargy and Fatigue
  2. Muscle Pain
  3. Headaches and Migraines

MYO LGD Ligandrol LGD 4033

MYO LGD Ligandrol LGD 4033

MYO LGD Ligandrol LGD 4033 is a cutting-edge SARM known for its remarkable ability to supercharge athletic performance and fuel muscle growth. This powerful compound not only enhances energy levels but also facilitates muscle building, aids in burning body fat, and boosts physical endurance.

Ligandrol Overview Table

An overview table with essential features of MYO LGD Ligandrol LGD 4033 is given below:

FeaturesLigandrol LGD 4033
Mechanism of ActionSkeletal muscle and bones promote muscle growth and bone density without significantly affecting other tissues.
Common UsesMuscle-building and strength enhancement for athletes and bodybuilders.
Dosage5 to 15 mg daily
Cycle Length8 weeks
StakesRAD-140 (Testolone), MK-677 (ibutamoren)
BenefitsIncreased muscle mass and strength, Enhanced endurance and recovery,Improved bone density, Fat loss
Side EffectsAcne, hair loss, aggression, cardiovascular, liver issues
Men / WomenBoth
PCT RequirementYes
Price89.99 CAD


  1. Elevated Testosterone Production
  2. Laser-Focused Workouts
  3. Boundless Energy
  4. Unstoppable Endurance
  5. Strength & Lean Muscle


  1. Liver Strain
  2. Dry Mouth
  3. Hair loss

Five Serious Side Effects of SARMs

Five Serious Side Effects of SARMs

There are five serious side effects of SARMs for bodybuilding you need to know:

1. Liver injury

According to “Selective Androgen Receptor Modulator Induced Hepatotoxicity by Sohaib Khan” SARMs, like other performance-enhancing compounds, exert stress on the liver. Elevated liver enzymes and liver injury are potential side effects, especially when taken in high doses or over extended periods.

2. Heart attack

According to “FDA Warns of Use of Selective Androgen Receptor Modulators (SARMs) Among Teens, Young Adults by James T Dalton” SARMs cause an increase in blood pressure. Elevated blood pressure poses a grave risk, potentially triggering heart attacks and cardiovascular complications. This danger escalates with prolonged or high-dose SARM usage.

3. Chronic infection

According to “Selective androgen receptor modulators: the future of androgen therapy by Andrew R. Christiansen” SARMs can compromise the immune system, making your body more susceptible to chronic infections. This weakening of your body’s defence mechanisms is particularly concerning for athletes who need to stay in peak physical condition.

4. Mood swings

According to “Adverse effects and potential benefits among selective androgen receptor modulators users: a cross-sectional survey by Iakov V Efimenko” Hormonal fluctuations caused by SARMs can lead to mood swings and emotional instability. Users have reported feeling irritable, anxious, or even experiencing depression during and after Selective Androgen Receptor Modulator cycles.

5. Acne

For many bodybuilders, acne is more than just a cosmetic concern. SARMs can stimulate oil production in the skin, potentially causing or exacerbating acne. 

What is the Least Potent SARM?

What is the Least Potent SARM?

The least potent SARM on the market is often considered to be Ostarine. It is especially true for beginners or individuals seeking subtle gains with minimal side effects. Ostarine is renowned for its ability to promote lean muscle growth and aid in fat loss.

Which SARMs Are the Most Harmful to the Body?

The SARM that poses the most significant risks to the body is Andarine S4. This compound has garnered attention for its potential to cause liver damage, as well as an increased risk of heart attack and stroke.

How Do You Cycle SARMs Safely?

To cycle SARMs safely, you should follow some essential steps. Begin with a conservative dosage and gradually increase it to gauge your body’s response. Stick to an 8-12 week cycle, ensuring you take breaks between cycles for proper recovery. Maintain a realistic training regimen, neither slacking off nor pushing too hard too quickly.

Prioritize healthy meal plans, never skipping meals or neglecting pre and post-workout nutrition. Tailor your Selective Androgen Receptor Modulator dosage to your needs and always follow up with post-cycle therapy.

Read more: How to Take SARMS Safely

What are the Safest SARMs for Bulking?

There are three safest SARMs for bulking include:

  1. Testolone RAD-140
  2. Ligandrol LGD-4033
  3. Ibutamoren MK-677

What are the Safest SARMs for Cutting?

There are the three safest SARMs for cutting are given below:

  1. Stenabolic SR-9009
  2. Cardarine GW-501516
  3. Ostarine MK-2866

What is the Safest SARM for Fat Loss?

The safest SARM for fat loss is Cardarine. When it comes to shedding those extra pounds, Cardarine stands out as the most effective option. It not only aids in fat loss but also safeguards your valuable muscle mass. Additionally, it maintains your strength and endurance at their peak levels.

What are the Safest SARMs for Beginners?

What are the Safest SARMs for Beginners?

Here are the three safest SARMs for beginners to consider:

  1. MK677 – Known for minimal testosterone suppression
  2. Cardarine – With hardly any side effects to worry about
  3. Ostarine – Prized for its fewer side effects compared to other options

What are the Safest SARMs for Women?

Here we discover the three top choices for safe SARMs tailored for women:

  1. Ostarine Mk2866
  2. Cardarine GW-501516
  3. Stenabolic SR9009


How Do Selective Androgen Receptor Modulators Work?

SARMs function by precisely targeting particular androgen receptors within your body, with a particular emphasis on your skeletal muscle tissue. These androgen receptors are distributed across various body parts, including the liver, muscle tissue, prostate gland, and bones.

According to “Selective Androgen Receptor Modulators (SARMs) – Current Knowledge and Clinical Applications by Zachary J. Solomon” SARMs stand out by precisely locking onto androgen receptors, guided by their distinct chemical blueprints. SARMs pinpoint precision unlocks muscle growth and enhanced performance, sparking fascination in the fitness and sports realms.

What is the Safest SARM for Athletes?

The safest SARM for athletes is Ostarine. Athletes have utilized Ostarine at lower doses with a decent safety profile, though precautions are still necessary. Athletes opt for its lower doses, enhancing performance and muscle gains. Beginners and intermediate Athletes in the world of Selective Androgen Receptor Modulators particularly favour Ostarine.

How Do SARMs Build Lean Muscle Mass and Burn Body Fat

SARMs work their magic by selectively targeting and binding to specific androgen receptors in our muscles and bones. Unlike traditional steroids with their wide-ranging and often unwanted effects, SARMs precisely target their actions.

By stimulating these receptors, SARMs prompt the body to build lean muscle mass, aiding in muscle growth and strength development. Moreover, they boost metabolism and promote fat-burning for energy during workouts.

What Can I Expect After a SARMs Cycle?

You can expect significant improvements in muscle mass and strength. SARMs are renowned for their ability to help users gain lean muscle without the extreme side effects associated with traditional steroids. You might experience enhanced endurance and quicker post-workout recovery, which can help you maintain your newfound gains.

SARMs Vs Anabolic Steroids: Which One is Safer?

According to “Systematic Review of Safety of Selective Androgen Receptor Modulators in Healthy Adults: Implications for Recreational Users by Jonathan D. Vignali” In terms of safety, recent clinical data unequivocally indicates that SARMs are safer than anabolic steroids. They boast significant short-term side effects and long-term benefits, making them the preferred choice.

Read more here: Differences between SARMs and Anabolic Steroids

What is the Safest Way to Buy SARMs?

What is the Safest Way to Buy SARMs?

The safest way to buy SARMs is online. provides a secure platform for purchasing high-quality products. It ensures a reliable source for your SARM needs at competitive prices.

Final Thoughts

RAD-140, Ibutamoren Mk 677, and Ligandrol (LGD-4033) stand out as top choices for their potent muscle-building properties and relatively low risk of adverse effects. These compounds excel at fostering lean muscle growth, boosting strength, and optimizing performance. They do so while prioritizing safety, minimizing the chance of unwanted side effects.

Safety and responsible usage should always be a top priority when considering SARM supplementation. With the right approach, you can harness the potential of SARMs to help you reach your fitness goals safely and effectively.


  • Ellis Hall and Misha F. Vrolijk (July 26, 2023) Androgen Receptor and Cardiovascular Disease: A Potential Risk for the Abuse of Supplements Containing Selective Androgen Receptor Modulators
  • Michael D. Nyquist, Lisa S. Ang, Alexandra Corella, Ilsa M. Coleman, Michael P. Meers, Anthony J. Christiani, Cordell Pierce, Derek H. Janssens (May 17, 2021) Selective androgen receptor modulators activate the canonical prostate cancer androgen receptor program and repress cancer growth
  • Megumi Morimoto, Masuo Yamaoka, Takahito Hara (Feb 7, 2020) A selective androgen receptor modulator SARM‐2f activates androgen receptor, increases lean body mass, and suppresses blood lipid levels in cynomolgus monkeys
  • Katsumi Kadekawa, Naoki Kawamorita, Takahiro Shimizu, Masahiro Kurobe (March 20, 2020) Effects of a Selective Androgen Receptor Modulator (SARM), GSK2849446A, on Stress Urinary Incontinence and Bladder Activity in Rats with Ovariectomy-induced Estrogen Deficiency
  • Haseeb Mohideen, Hafsa Hussain, Dushyant Singh Dahiya, Hisham Wehbe (Nov 4, 2022) Selective Androgen Receptor Modulators: An Emerging Liver Toxin
  • Wenqing Gao, James T. Dalton (Feb 7, 2007) Expanding the therapeutic use of androgens via selective androgen receptor modulators (SARMs)
  • Ankit Desai, Musaab Yassin, Axel Cayetano, Tharu Tharakan, Suks Minhas (June 26, 2022) Understanding and managing the suppression of spermatogenesis caused by testosterone replacement therapy (TRT) and anabolic–androgenic steroids (AAS)
  • Wael T Mohamed, Vinay Jahagirdar, Ifrah Fatima, Mohamed K Ahmed, Fouad Jaber (Feb 17, 2023) Selective Androgen Receptor Modulators (SARMs)-Induced Liver Injury: A Case Report and Review of Literature

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