Testosterone Enanthate Review: Uses, Benefits and Side Effects

Testosterone Enanthate is a cornerstone in many bodybuilders’ regimens and is renowned for its muscle-building prowess. This synthetic form of testosterone enhances protein synthesis, promoting the growth of lean muscle mass and aiding recovery. Bodybuilders often favour its long-lasting effects, requiring fewer injections. 

As an injectable form of the hormone, it is gradually released into the bloodstream, offering sustained benefits. This guide will discuss the uses, potential benefits, and, crucially, the side effects of Testosterone Enanthate.

What is Testosterone Enanthate?

Testosterone Enanthate is a synthetic testosterone used in bodybuilding to enhance muscle growth and performance. Its chemical structure is C26H40O3.

The chemical structure of testosterone enanthate is quite similar to other testosterone forms. The enanthate ester chain, which is linked to the 17-beta hydroxyl group of the testosterone molecule, is the sole major difference.

Initially employed in androgen replacement therapy, Testosterone Enanthate has evolved to become a cornerstone in treating hypogonadism.

It is also utilized in addressing delayed puberty in boys and, remarkably, even breast cancer in women. Testosterone Enanthate enhances muscle growth, strength, and overall athletic performance in bodybuilding. 

Administered through injections, Testosterone Enanthate accelerates recovery and enhances protein synthesis. Additionally, it boosts red blood cell production, facilitating significant gains in muscle mass and power.

How Does Testosterone Enanthate Work?

How Does Testosterone Enanthate Work?

Testosterone Enanthate functions by closely mimicking the actions of natural testosterone in the body. This potent bodybuilding steroid significantly supports muscle mass development, increased strength, and better endurance.

Acting as a synthetic form of testosterone enhances protein synthesis, facilitating the efficient growth and repair of muscle cells. 

Users experience a notable surge in energy levels and stamina, allowing for intense and prolonged workouts. The anabolic properties of Testosterone Enanthate enable individuals to achieve peak physical performance while building muscle.

Testosterone Enanthate Use Cases

Testosterone Enanthate finds widespread application in addressing medical conditions such as low testosterone and delayed puberty, primarily among males. Additionally, it serves as a therapeutic option for females combating breast cancer. 

According to “Changes in Muscle Mass, Muscle Strength and Power, but not Physical Function are Related to Testosterone Dose in Healthy Older Men by Thomas W. Storer” Beyond its medical realm, bodybuilders often turn to this synthetic testosterone variant to amplify muscle growth and elevate performance levels. 

Administered through intramuscular injections, its gradual release ensures a sustained anabolic impact. It fosters essential processes like nitrogen retention and protein synthesis, which are pivotal for robust muscle development.

Testosterone Enanthate for Bodybuilders

Administered through regular injections, this synthetic form of testosterone offers various benefits for those aiming to enhance their physique.

Increased muscle mass, improved strength, and accelerated recovery are critical advantages of Testosterone Enanthate use. Its anabolic properties contribute to muscle protein synthesis, aiding in lean muscle development.

Moreover, the hormone promotes nitrogen retention, which is crucial for sustaining an anabolic environment. Bodybuilders often find that consistently using Testosterone Enanthate leads to heightened training intensity and more efficient results in their pursuit of muscle hypertrophy.

Related: Testosterone 400 for Bodybuilders

Optimal Testosterone Enanthate Dosage

A common starting point for therapeutic use is 250 to 400 milligrams every two weeks. Bodybuilders aiming for performance enhancement might use higher doses, typically 500 to 1000 milligrams weekly.

Testosterone Enanthate Cycle

Administered through intramuscular injections every eight to twenty weeks, this synthetic form of testosterone aids in combating symptoms like fatigue and low libido.

Beginners Cycle

A minimum 8-10 week cycle is recommended for beginners.

Advanced Cycle

An advanced cycle for bodybuilders typically spans 12 to 20 weeks. This extended duration is designed for seasoned individuals seeking enhanced muscle gains and performance. The prolonged cycle allows for a gradual and sustained progression, minimizing abrupt changes that may stress the body.

Best Testosterone Enanthate Stacks for Bodybuilding

Table of Best Testosterone Enanthate Stacks for Bodybuilding:

Steroid CombinationDosageCycle Duration
Testosterone Enanthate + Deca Durabolin500mg/week + 400mg/week12-16 weeks
Testosterone Enanthate + Trenbolone Acetate500mg/week + 75mg every other day10-12 weeks
Testosterone Enanthate + Anavar (Oxandrolone)500mg/week + 50mg/day8-10 weeks
Testosterone Enanthate + Dianabol500mg/week + 30mg/day6-8 weeks
Testosterone Enanthate + Masteron500mg/week + 400mg/week10-12 weeks

5 Benefits of Testosterone Enanthate for Bodybuilding

5 Benefits of Testosterone Enanthate for Bodybuilding

There are five expected benefits of Testosterone Enanthate for Bodybuilding are given below:

1. Increased Muscle Mass

Testosterone Enanthate is known to stimulate protein synthesis, leading to an increase in muscle tissue. This benefit is crucial for bodybuilders aiming to enhance their overall muscle mass.

2. Improved Recovery Time

Users of Testosterone Enanthate may experience faster recovery times between intense workouts. It can contribute to more frequent and rigorous training sessions.

3. Enhanced Strength

Elevated testosterone levels can increase strength, allowing bodybuilders to lift weights and push their physical limits during training.

4. Improved Libido & Sexual Performance

Improved libido can enhance overall sexual satisfaction, fostering closer emotional connections between partners. It contributes to better mental well-being, reducing stress and anxiety. Increased libido also promotes better sleep quality, positively impacting overall health.

5. Improved Bone Density

Higher testosterone levels have a positive impact on bone mineral density. It can benefit bodybuilders, as stronger bones provide a solid foundation for muscle development.

Testosterone Enanthate Results Before and After

A moderate dose of 500mg per week over 12 weeks has shown a significant increase in lean muscle mass, with users experiencing substantial gains of up to 10 pounds or more.

Similarly, a 10% reduction in body fat has been observed in individuals following a 300mg per week dosage for an 8-week cycle. 

These outcomes underscore the impact of tailored Testosterone Enanthate use on body composition within defined time frames.

5 Side Effects of Testosterone Enanthate for Bodybuilding

5 Side Effects of Testosterone Enanthate for Bodybuilding

Five common side effects of Testosterone Enanthate for Bodybuilding are given below:

1. Cardiovascular Risks

Elevated levels of testosterone can contribute to an increase in red blood cell count, cholesterol levels, potentially leading to higher blood viscosity and a greater risk of cardiovascular issues.

Individuals with a history of heart disease, liver or renal issues, or high blood pressure should refrain from the use of testosterone enanthate.

2. Hormonal Imbalance

Testosterone Enanthate supplementation can disrupt the body’s natural hormonal balance. According to “Localized Rhabdomyolysis Associated With Testosterone Enanthate for Gender-Affirming Hormonal Therapy by Rashmi Reddy,” Excessive testosterone levels can lead to the suppression of the body’s testosterone production. This imbalance may affect mood, libido, and overall well-being.

3. Liver Strain

The liver is crucial in metabolizing bodily substances, including synthetic hormones. According to “Effect of Testosterone Enanthate Modeling of Polycystic Ovary on Liver Irs-2 mRNA Expression in Rats: A Brief Report by Seyyed Amir Yasin Ahmadi,” Using Testosterone Enanthate may strain the liver, especially with prolonged or excessive use. Monitoring liver function is crucial to address potential complications.

4. Acne and Skin Issues

An increase in testosterone levels can stimulate sebum production, leading to acne and skin-related problems. According to “Male Contraception: Clinical Assessment of Chronic Administration of Testosterone Enanthate by Ronald S. Swerdloff,” Bodybuilders using Testosterone Enanthate may experience breakouts and oily skin due to hormonal changes.

While testosterone may play a role in hair loss in those who are genetically prone to male pattern baldness, it is not the only reason. In fact, many testosterone enanthate users report increased hair growth as a result of the hormone’s capacity to promote the creation of new hair follicles.

5. Gynecomastia

An imbalance in testosterone levels can lead to gynecomastia, the development of breast tissue in males. These estrogen related side effects is a result of elevated estrogen levels relative to testosterone, often requiring medical intervention for correction.

Related: Potential risks of Testosterone shots

Testosterone Enanthate vs Testosterone Cypionate vs Testosterone Propionate

Here is a comparison table of testosterone enanthate, testosterone cypionate and testosterone propionate:

AspectsTestosterone EnanthateTestosterone CypionateTestosterone Propionate
BenefitsIncreased muscle mass, Enhanced strength, Improved libidoImproved muscle strength, Boost in stamina, Positive mood effectsEnhanced muscle definition, Increased vascularity, Rapid recovery
Side EffectsCough, shortness of breath, chest pain, dizzinessAcne, pain, hair growth, gynecomastia, mood swings, headacheSweating, headache, acne, breast pain, and gynecomastia
Half Life~8 days~8 days~2 days
Dosage250-500 mg per week250-500 mg per week50-100 mg per day
Cycle Length6 – 8 weeks10-12 weeks8-10 weeks
Peak LevelsReached after one or two daysReached after one or two daysQuickly achieved
StabilityStable blood levelsStable blood levelsFluctuating blood levels


What is the Best Testosterone Ester for Bodybuilding?

Testosterone Cypionate stands out as an optimal choice. Administered every one to two weeks, this long-acting ester releases testosterone gradually, ensuring a sustained impact on muscle development and performance.

Can You Take Testosterone Shots Without a Prescription?

Yes, you can obtain testosterone shots without a prescription. However, self-administering hormonal treatments without medical supervision poses significant risks. Unregulated use may lead to adverse effects, including cardiovascular issues and hormonal imbalances.

Does Testosterone Injection Reduce Natural Testosterone Production?

Yes, Testosterone injections can suppress natural testosterone production. When external testosterone is introduced, the body may interpret it as sufficient and signal a reduction in endogenous production.

This is why careful monitoring and management by healthcare professionals are crucial during testosterone replacement therapy to maintain hormonal balance and avoid unintended consequences.

Testosterone Enanthate vs Sustanon: Which One is Better for Bodybuilding?

Testosterone Enanthate is superior for bodybuilding when compared to Sustanon. Its single ester composition provides a more stable and consistent release of testosterone compared to the varied blend found in Sustanon.

This stability allows for easier management of hormone levels, promoting muscle growth and performance gains.

How fast does testosterone enanthate work?

It usually takes 42 days, but it can take up to 84 days to see any results. According to this research, the use of testosterone enanthate has been demonstrated to considerably enhance strength within 6-12 weeks of administration. Although it is unknown if the ergogenic advantages are seen in less than 6 weeks.

What is the fastest acting testosterone?

Testosterone Propionate. It is the most rapidly acting testosterone ester. It normally reaches a peak in the blood within hours and might be completely digested within three days. Injections are usually given every 2-3 days to keep levels stable.

Where can I buy Test E for bodybuilding online in Canada?

You can buy Test E for bodybuilding online in Canada from BuyRoidsCanada. They are the no#1 source for buying anabolic steroids online. You can buy any popular anabolic steroid without any hesitation. All of their products are selected after thorough research and lab testing. In addition, you will receive your delivery within 24 hours safely anywhere in Canada.

Final Thoughts

Testosterone Enanthate is a synthetic form of testosterone. It boosts muscle growth and strength, enhances mood, and increases libido. Administered through injections, the standard dosage is 250-1000mg weekly. Typical Testosterone Enanthate cycles typically last 8-20 weeks. Benefits include improved muscle mass and athletic performance. 

However, usage of this controlled substance has been related to a number of health problems, including cardiovascular disease, liver damage, and kidney damage.

Maintain the recommended dosage at all times and seek professional advice to prevent potential risks while reaping significant benefits. Proper post-cycle therapy is crucial to restore natural testosterone production.

Stakes are high when misused, risking health complications. Always consult a healthcare professional before embarking on Testosterone Enanthate use.


  • The effect of short-term use of testosterone enanthate on muscular strength and power in healthy young men (May 21, 2007) Shane Rogerson, Robert P Weatherby, Glen B Deakin, Rudi A Meir, Rosanne A Coutts, Shi Zhou, Sonya M Marshall-Gradisnik
  • Metabolomics of testosterone enanthate administration during severe-energy deficit (November 30, 2022) J. Stein, J. Karl, Claire E. Berryman, Melissa Harris, J. Rood, S. Pasiakos, H. Lieberman
  • Neutralising the testosterone enanthate-induced oxidative stress in rats uterine tissue by propolis and chicory as natural antioxidants (December 2, 2022) W. Liu, M. Akbarpour-Beni, S. Movahed, A. Gorzi, E. Cheraghi, H. Amini
  • The Effect of Eight Weeks of Testosterone Enanthate Consumption on Oxidative Indicators of Kidney Tissue in Resistance Trained Rats (December 30, 2020) Masoumeh Mehrabi, Y. Kazemzadeh, A. Gorzi, S. Hosseini, S. Sedaghati
  • Risks of testosterone replacement therapy in men (Jan-Mar, 2014) E. Charles Osterberg, Aaron M. Bernie, and Ranjith Ramasamy

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