SARMs PCT Guide: How to Use SERM & Aromatase Inhibitors

Post-cycle therapy (PCT) is a protocol you undertake after completing a SARM cycle. Rejuvenate your body’s low testosterone levels, counteracting selective androgen receptor modulators (SARMs) suppressive effects.

Key Takeaway

  • SARMs such as Ostarine, Ligandrol, and Andarine require Post-Cycle Therapy (PCT) due to testosterone suppression.
  • A typical PCT regimen typically lasts 4-6 weeks and should be started promptly after the SARM cycle to restore hormonal balance and minimize disruptions.
  • Clomid, Nolvadex, HCG, Savage PCT, and Anastrozole are effective options for restoring hormonal balance and maintaining muscle gains.

This downturn could lead to undesirable consequences, such as decreased libido, fatigue, and mood swings, potentially hindering your fitness and muscle upkeep. Hence, PCT becomes essential, especially after using stronger SARMs.

PCT regimen involves a two-week high-dose phase, followed by a reduced dosage phase of 2 to 4 weeks. In this blog post, we’ll dive into the best PCT options for SARMs, how to take PCTs after a cycle, the duration of supplementation, and a reliable source for SARMs PCT supplements in Canada.


SARMs suppress your body’s testosterone production. PCT aids your body in recovering, letting it return to normal testosterone levels. It helps you transition smoothly and stay healthy. 

A good PCT cycle lowers estrogen levels and restores natural testosterone, rebalancing your hormones. If you use steroids, this regulated hormone healing is a clear choice.

How SARMs Work?

SARMs work by binding to androgen receptors in the body. It boosts levels of testosterone, promoting muscle growth and strength. They are illegal, and the CFIA hasn’t approved them for human use. These compounds promise to maintain gains and reduce side effects compared to traditional steroids. SARMs target specific tissues, minimizing potential harm to other organs.

How PCT Works for Maintaining Gains and Reducing Side Effects?

How PCT Works for Maintaining Gains and Reducing Side Effects?

According to “Support for people who use Anabolic Androgenic Steroids: A Systematic Scoping Review into what they want and what they access by Orlanda Harvey, Steve Keen, Margarete Parrish, and Edwin van Teijlingen” Post Cycle Therapy works by restoring the hormonal balance within the user’s body. One primary goal is to reduce estrogen levels that might have increased during the cycle. PCT revitalizes your body’s levels of testosterone without any testosterone booster, ensuring lasting gains and minimizing side effects.

Two Types of SARMs PCT Supplement

Types of SARMs PCT Supplement

There are two types of SARMs PCT. They are:


SERM, or Selective Estrogen Receptor Modulator, is a compound that functions similarly to SARMs but with a focus on estrogen receptors. These molecules compete against estrogen at these receptors, binding to them and preventing estrogen from exerting its effects.

As a result, estrogen production and its related effects decrease. SERMs also influence the pituitary gland and hypothalamus, supporting healthy levels of luteinizing and follicle-stimulating hormones. 

For Example, SERMs like Tamoxifen, Nolvadex, Clomiphene citrateare used in bodybuilding to counteract estrogen-related side effects from anabolic steroid use. 

They bind to estrogen receptors, preventing excessive estrogen activity, thus reducing gynecomastia and water retention. It supports lean muscle gains and a more defined physique during cycles.

Aromatase Inhibitor

Aromatase inhibitors (AI) are medications that block the conversion of testosterone into estrogen. This helps control estrogen levels, which can be important in managing conditions like certain types of breast cancer or hormonal imbalances. In bodybuilding, these inhibitors are used to reduce side effects caused by anabolic steroid use, such as gynecomastia (breast enlargement) and water retention.

By keeping estrogen levels in check, bodybuilders aim to achieve better muscle definition and reduce bloating during competitions. Common AI used in bodybuilding include Anastrozole, Exemestane, and Letrozole.

Which SARMs Require PCT and Which Do Not?

Which SARMs Require PCT and Which Do Not?

These three compounds needing PCT include:

  1. MK-2866 (Ostarine)
  2. LGD-4033 (Ligandrol)
  3. S4 (Andarine)

These SARMs can suppress natural testosterone production, necessitating post-cycle therapy to help restore hormonal balance.

These two SARMs do not require post-cycle therapy:

  1. MK-677 (Ibutamoren)
  2. GW-501516 (Cardarine)

Don’t require post-cycle therapy, as they don’t significantly impact testosterone levels.

What are the Best PCT For SARMs?

Let’s now examine the top five most effective SARMs PCT options and explore the reasons behind their status as the best choices:

Clomid (Clomiphene)

Clomid (Clomiphene)

Clomiphene, known as Clomid, offers potent SERM benefits with a slight trade-off in temporary nausea. Its mechanism involves competing against estradiol at estrogen receptor sites in the hypothalamus, curbing estrogen’s effects.

This effectiveness arises from its ability to boost FSH (Follicle Stimulating Hormone) and LH (Luteinizing Hormone) levels, restoring testosterone and elevating androgens. The optimal for substantial testosterone suppression is 50 mg to 100 mg daily. Its effects become noticeable after approximately two weeks, leading to a gradual dose reduction over the next 2 to 4 weeks.

Nolvadex (Tamoxifen)

Nolvadex (Tamoxifen)

Nolvadex, or Tamoxifen, is a SERM frequently employed in Post Cycle Therapy (PCT) by bodybuilders after completing a steroid cycle. Acting as an Estrogen antagonist, its main role is countering the undesirable effects of estrogen in the body. While it operates as an estrogen agonist, much like estrogen itself, it serves a vital purpose.

According to “Tamoxifen for prevention of breast cancer: report of the National Surgical Adjuvant Breast and Bowel Project P-1 Study Nolvadex is integral in PCT and finds use in breast cancer treatment. Curtailing estrogen levels effectively prevents the spread of cancer, particularly in the breast region. Tamoxifen’s heightened potency makes it a frequent partner with Clomid in PCT.

Human Chorionic Gonadotropin (Hcg)

Human Chorionic Gonadotropin (Hcg)

Human Chorionic Gonadotropin (HCG) is often employed during and after steroid cycles to counteract the effects of anabolic androgenic steroids (AASs). These steroids signal the hypothalamus, prompting a decrease in gonadotropin-releasing hormone (GnRH) and testosterone suppression.

Bodybuilders use HCG to maintain and restore testicular size. It supports the return of normal testosterone levels and prevents unwanted side effects.

Savage PCT

Savage PCT

Savage PCT is a bodybuilding supplement designed to boost testosterone production, enhance libido, and support quick recovery after your SARMS or steroid cycle. Tailored for bodybuilders, this product aids in maintaining gains and hormonal balance. By stimulating testosterone, it assists muscle mass and overall performance. Its emphasis on rejuvenation can effectively combat the impacts of post-cycle fatigue.



Anastrozole for bodybuilding serves as an honourable mention among PCT for SARMs. While SERMs excel in countering gyno and testosterone decline, anastrozole is an aromatase inhibitor. By halting testosterone conversion breakdown, it reduces estrogen levels.

Unlike SERMs, it doesn’t rapidly decrease estrogen but supports testosterone elevation. Effective against gyno and mild testosterone drop, the dosage starts at 1 mg weekly, tapering to 0.5 mg daily until issues resolve.

Why You Must Take PCT Supplements After a SARM Cycle

Why You Must Take PCT Supplements After a SARM Cycle

Below, we will discuss five reasons to consider taking a PCT supplement after completing a SARMs cycle:

1. Balance Hormones

SARMs can mess with your hormones. PCT supplements help bring them back to normal.

2. Keep Gains

After a SARM cycle, you want to keep the muscle mass you gained. PCT supplements help maintain your progress.

3. Boost Energy

SARM cycles can leave you feeling tired. PCT supplements might bring back your energy.

4. Regain Natural Testosterone Levels

You may see testosterone drop after a SARMs cycle. PCT supplements are designed to mitigate the extent of testosterone suppression and restore testosterone levels to their baseline.

5. Support Your Recovery

SARMs can leave you a little drained. PCT for SARMs help speed up your recovery so you can return to workouts sooner. 

What Happens When You Don’t Use a PCT?

According to “Recovery of spermatogenesis following testosterone replacement therapy or anabolic-androgenic steroid use by J Abram McBride and Robert M Coward” Skipping Post Cycle Therapy following anabolic steroid use makes it challenging for your natural testosterone production to recover. It leads to the potential loss of your diligently earned muscle gains. PCT helps your body regain its hormonal balance and maintains your gains.

How to Take PCTs After a SARM Cycle?

After completing a SARM cycle, it’s recommended to take post-cycle therapy (PCT) to help restore natural hormone levels. The specific PCT protocol depends on the SARMs used and the dosage. Generally, for a mild PCT cycle, you might use Nolvadex (tamoxifen) at 20mg daily for 4 to 6 weeks. For a stronger process, a combination of Nolvadex and Clomid (clomiphene) could be used.

How Long Should You Take PCT Supplement to Reduce Side Effects of SARMs

It involves a 4-week regimen. Beginning your post-cycle therapy promptly helps restore hormonal balance and minimize potential disruptions caused by SARM usage.

Where to Buy the Best SARMs PCT in Canada?

For the best SARMs PCT in Canada, look no further than This reliable online shop offers a wide range of high-quality PCT to support your fitness journey. With our reputable products and easy ordering process, you can find the right PCT solution to aid your post-cycle recovery effectively.

Related article: Best SARMs for Bulking and Best SARMs for Cutting


Why Do SARMs Suppress Testosterone?

SARMs suppress testosterone due to their specific interaction with androgen receptors. While designed to target muscle and bone tissue, some SARMs can inadvertently disrupt the endocrine system’s natural feedback loop. This interference signals the body to lower testosterone production, causing potential hormonal imbalances.

Can I start my PCT cycle 3 days later after my SARMs cycle?

Yes, you may begin immediately after discontinuing selective androgen receptor modulators (SARMs) and prohormones. When using steroids, it is best to wait a week before beginning PCT. In an ideal world, you would seek the advice of a skilled doctor to establish a treatment plan and monitor your progress.

What Are the Differences Between SERMs and Aromatase Inhibitors?

SERMs prevent estrogen receptor (ER) signalling by binding to the ER and forming an inactive complex. Aromatase inhibitors stop estradiol production, a hormone that fuels certain cancers.

Are SARMs Safer Than Anabolic Steroids?

Due to their selective impact on specific body receptors, SARMs are often considered safer than steroids, resulting in fewer side effects. SARMs focus on particular tissues, offering potential benefits. Unlike anabolic steroids, they aim to minimize risks, which can cause liver damage and hormonal imbalances.


How to Minimize the Side Effects of SARMs?

To minimize SARMs’ side effects, adhere to recommended doses and cycle length, especially with Ostarine. Stick to the prescribed limits and avoid exceeding the cycle duration. It helps balance desired results and potential risks, ensuring a safer and more effective experience with SARMs.

Final Thoughts on the Best PCT for SARMs

SARMs PCT is essential to restore hormonal equilibrium after a SARMs cycle. Utilize post cycle therapy supplements like SERMs and aromatase inhibitors. They help neutralize the potential adverse effects of SARMs on hormone levels. It aids in maintaining your hard-earned gains, boosting energy levels, and expediting recovery.

Skipping PCT can hinder your natural testosterone recovery, leading to a loss of gains. SARMs like Ostarine, Ligandrol, and Andarine require PCT, while others like Ibutamoren and Cardarine do not significantly impact testosterone. The top PCT options include Clomid, Nolvadex, HCG, Savage PCT, and Anastrozole.

Following a 4-week regimen, promptly beginning PCT supports hormonal balance and minimizes disruptions from SARM usage. For the best SARMs PCT in Canada, offers high-quality options to aid your post-cycle recovery effectively.


  • Melissa A. Burmeister, PhD, Timothy K. Fincher, RPh, PhD, William H. Graham, PharmD (June 18, 2020) Recreational Use of Selective Androgen Receptor Modulators
  • Shalender Bhasin, MD and Ravi Jasuja (July 20, 2010) SARMs as Function Promoting Therapies
  • Tomas Koller, Petra Vrbova, Iveta Meciarova, Pavol Molcan, Michal Smitka, Svetlana Adamcova Selcanova, and Lubomir Skladany (Jun 6, 2021) Liver injury associated with the use of selective androgen receptor modulators and post-cycle therapy: Two case reports and literature review
  • Juice Lewis (July 2, 2023) Anabolic Steroids and SARMS Handbook for Bodybuilders and Athletes
  • Wael T. Mohamed, Vinay Jahagirdar, Ifrah Fatima, Mohamed K. Ahmed, Fouad Jaber, Kevin Wang, Amira Hassan, Eric Ewing, Wendell Clarkston, Alisa Likhitsup (February 17, 2023) SARMs-Induced Liver Injury: A Case Report and Review of Literature
  • Scott Griffiths, Richard Henshaw, Fiona H. McKay, Matthew Dunn (March 2, 2017) Post-cycle therapy for performance and image enhancing drug users: A qualitative investigation

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